2021 Scientific Program

8:50-9 AM
Welcome and Introduction to the Symposium
Jeremy Ruskin, MD

9-9:55 AM
I. AF SCREENING, MONITORING and RISK FACTOR MODIFICATION I
Moderator: Christine Albert, MD
Digital Moderator: Andrea Russo, MD

Implantable Monitors vs Wearables vs Pulse Checks for AF Detection
Mintu Turakhia, MD

Artificial Intelligence-Electrocardiography to Predict Incident AF
Peter Noseworthy, MD

Genetic Profiling in AF Screening - Predicting Outcomes
Steven Lubitz, MD

How Accurate are Predictive Scores for AF Ablation Outcomes?
Isabel Deisenhofer, MD

Panel and Audience Discussion (20 minutes) - All Faculty

9:55-11 AM
II. AF SCREENING, MONITORING and RISK FACTOR MODIFICATION II
Moderator: Jeremy Ruskin, MD
Digital Moderator: Mina Chung, MD

Role of Epicardial Adipose Tissue in Persistent AF: Impact on Ablation Outcomes
Young-Hoon Kim, MD, PhD

Electrophysiological Effects of Obesity
Jonathan Kalman, MD

Sex Differences in AF Outcomes (Ablation, Stroke, Anticoagulation)
Andrea Russo, MD

Risk Factors for AF - Who, When and How to Intervene
Eric Prystowsky, MD

2020 ESC Guidelines for AF Management: What’s New?
Gerhard Hindricks, MD

Panel and Audience Discussion (25 minutes) - All Faculty

11 AM-1:10 PM
III. REAL-TIME and PRERECORDED CASE TRANSMISSIONS I
Moderator: Vivek Reddy, MD
Digital Moderator: David Keane, MD, PhD
Panel: John Hummel, MD and Pierre Jais, MD

Pulsed Field Ablation with a Circular Multielectrode Catheter
Tom De Potter, MD, OLV Hospital, Aalst, Belgium

Pulsed Field Ablation with an Over-the-Wire Catheter System
Atul Verma, MD, Southlake Regional Health Centre, Toronto ON

New Generation Left Atrial Appendage Closure Device
Moussa Mansour, MD, Massachusetts General Hospital, Boston, MA

Global Substrate Mapping and Targeted Ablation with Novel Gold-Tip Catheter in De Novo Persistent AF
Tim Betts, MD, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Panel and Audience Discussion During Cases

1:10-1:30 PM
BREAK

1:30-2:30 PM
IV. ATRIAL FIBRILLATON in PATIENTS with HEART FAILURE and PRESERVED EJECTION FRACTION
Supported by an educational grant from Abbott Medical
Moderator: Larry Chinitz, MD
Digital Moderator: Meleze Hocini, MD

AF in HFpEF vs HFrEF: Prevalence, Prognosis, and Impact on HF Therapies
Hugh Calkins, MD

Atrial Dysfunction in HFpEF: Relationship to AF Burden, Pulmonary Vascular Disease, Right Heart Failure, and Mortality
Barry Borlaug, MD

Optimized Hemodynamic Management of HFpEF for Prevention of AF and Improved Survival
Rahul Doshi, MD

Safety, Efficacy and Prognostic Benefit of AF Ablation in HFpEF
Dipen Shah, MD

Principles and Clinical Use of Omnipolar Intracardiac Electrogram Analysis
John Day, MD

Left-Right Atrial Isolation & LAA Closure in Patients with AF & End-Stage Atrial Myopathy
Yan Huo, MD PhD

Panel and Audience Discussion (20 minutes) - All Faculty

2:30-2:40 PM
BREAK

2:40-3:40 PM
V. EARLY STAGE and EMERGING NEW TECHNOLOGIES and DRUGS in CARDIAC EP I
All Talks 5 Minutes
Moderator: Jeremy Ruskin, MD
Digital Moderator: Paul Wang, MD

Ablacon - Atul Verma, MD
Acesion Pharma - John Camm, MD
Acutus - Usman Siddiqui, MD
BioSig - Joseph Gallinghouse, MD
CardiaCare - Vivek Reddy, MD
CardioNXT - Bobby Kurian, MD
EPD Solutions - Tom De Potter

Panel and Audience Discussion (20 minutes) - All Faculty

3:40-4:35 PM
VI. STROKE PREVENTION in AF – ANTICOAGULATION
Moderator: Elaine Hylek, MD
Digital Moderator: Pasquale Santangeli, MD

AF Duration and Stroke Risk: When and in Whom is Anticoagulation Indicated?
John Camm, MD

Pill-in-the-Pocket Anticoagulation for AF
Rod Passman, MD

Management of Anticoagulation after AF Ablation
Andrea Natale, MD

Cerebral Amyloid Angiopathy: Prevalence, Detection and Management
Mahmut Edip Gurol, MD

Panel and Audience Discussion (20 minutes) - All Faculty

4:35-5:40 PM
VII. STROKE PREVENTION in AF - LEFT ATRIAL APPENDAGE CLOSURE I
Moderator: Dhanujaya Lakkireddy, MD
Digital Moderator: Randall Lee, MD

Propensity Matching Analyses of NOACs vs LAAC
Jens Nielsen-Kudsk, MD

PRAGUE 17 Trial and Sub-Study Data
Pavel Osmancik, MD

New Devices for Endocardial and Epicardial LAA Closure
Dhanunjaya Lakkireddy, MD

Updates on Clinical Trials on LAA Closure
Christopher Ellis, MD

FDA Regulatory Perspective on New LA Appendage Closure Devices
Andrew Farb, MD

Panel and Audience Discussion (25 minutes) - All Faculty

5:40-6:35 PM
VIII. STROKE PREVENTION in AF - LEFT ATRIAL APPENDAGE CLOSURE II
Moderator: Douglas Gibson, MD
Digital Moderator: Mohan Nair, MD

Is LAA Closure First-Line in Patients with Major Contraindications to Anticoagulation
Devi Nair, MD

Periprocedural Antithrombotic Management in Patients with Bleeding-Related Contraindications
Walid Saliba, MD

Safety Issues in Left Atrial Appendage Closure: Management and Prevention
Jacqueline Saw, MD

NCDR Left Atrial Appendage Closure Registry Update
Zoltan Turi, MD

Panel and Audience Discussion (20 minutes) - All Faculty

6:35-7:30 PM
IX. LATE BREAKING CLINICAL TRIALS and FIRST REPORT CLINICAL INVESTIGATIONS
Moderator: Jeremy Ruskin, MD

Radiofrequency Ablation for Paroxysmal or Persistent Atrial Fibrillation Using a Lattice-Tip Catheter: The Effect of Durable Lesions on One-Year Freedom from Atrial Arrhythmias
Vivek Reddy, MD

Lattice-Tip Focal Ablation of Persistent Atrial Fibrillation: Toggling Between Pulsed Field and Radiofrequency Energy
Vivek Reddy, MD

Hybrid Epicardial-Endocardial Ablation vs. Endocardial Catheter Ablation for Longstanding Persistent Atrial Fibrillation Treatment: A Sub-Analysis from CONVERGE Multi-Center Randomized Controlled Trial
David DeLurgio, MD

Hybrid Thoracoscopic Surgical and Transvenous Catheter Ablation Versus Transvenous Catheter Ablation In Persistent And Longstanding Persistent Atrial Fibrillation: 1-Year Results of The HARTCAP-AF Randomized Controlled Trial
Bart Maesen, MD, PhD

Efficacy and Safety of Esophageal Deviation in Atrial Fibrillation Ablation Using an Inflatable Balloon: A Prospective Single-Arm Study
Weeranun D. Bode, MD

9-10:25 AM
X. EARLY RHYTHM CONTROL in ATRIAL FIBRILLATION
Moderator: David Wilber, MD and Albert Waldo, MD
Digital Moderator: Carlos Morillo, MD

New Outcomes of CABANA: One Year Later
Douglas Packer, MD

EAST-AFNET 4 Trial: Early Rhythm Control Therapy in AF
Paulus Kirchhof, MD

ATTEST Trial: Catheter Ablation to Modify Progression of AF
Karl-Heinz Kuck, MD

Catheter Ablation for Asymptomatic AF: Key Considerations
Francis Marchlinski, MD

First-Line Cryoablation Trials for PAF: STOP-AF FIRST, EARLY AF and CRYO-FIRST
Oussama Wazni, MD

Debate and Discussion: First Line Therapy for Atrial Fibrillation - Drugs or Ablation?
Treat AF Early with Catheter Ablation as First-Line Therapy - Jason Andrade, MD Treat AF Early with Antiarrhythmic Drugs as First-Line Therapy - Peter Kowey, MD

Panel and Audience Discussion (30 minutes) - All Faculty

10:25 AM-1 PM
XI. REAL-TIME and PRERECORDED CASE TRANSMISSIONS II
Moderator: Moussa Mansour, MD
Digital Moderator: David Keane, MD, PhD
Panel: Francis Marchlinski, MD and Isabel Deisenhofer, MD

Novel Cryoballoon System for Pulmonary Vein Isolation
Claudio Tondo, MD, PhD, University of Milan Centro Cardiologico Monzino, Milan, Italy

Treatment of Incomplete Left Atrial Appendage Closure
Dhanunjaya Lakkireddy, MD, HCA Midwest Health, Kansas City, KS

Ablation of Persistent AF - PVI Plus Adjunctive Ablation
Rodney Horton, MD and Andrea Natale, MD, Texas Cardiac Arrhythmia Institute, Austin, TX

Vein of Marshall Alcohol Ablation
Miguel Valderrabano, MD, Houston Methodist Hospital, Houston, TX

Non-contact Map Ablate Remap Strategy in Complex Atrial Arrhythmias
Dhanunjaya Lakkireddy, MD, HCA Midwest Health, Kansas City, KS

Panel and Audience Discussion During Cases

1-1:20 PM
BREAK

1:20-2:20 PM
XII. ACCELERATING the FUTURE of EP PROGRAMS and AF ABLATION
Supported by an educational grant from Biosense Webster
Moderators: Jose Osorio, MD
Digital Moderator: Usha Tedrow, MD

Same Day Discharge for Patients Undergoing AF Ablation: Prospective Selection Criteria and Safety Outcomes
Jose Osorio, MD

Monitoring for Arrhythmias after AF Ablation: The Why, Who, What, When and How
Rhea Pimentel, MD

Catheter Stability for an Efficient, Effective, and Safe PVI
Paul Zei, MD

Planning the Future of Electrophysiology: Trends and Gender-related Needs of Trainees
Usha Tedrow, MD

Panel and Audience Discussion (30 minutes) - All Faculty

2:20-2:30 PM
BREAK

2:30-3:30 PM
XIII: EARLY STAGE and EMERGING NEW TECHNOLOGIES and DRUGS in CARDIAC EP II
Moderator: Paul Wang, MD
Digital Moderator: Bradley Knight, MD

Cardiva Medical - David DeLurgio, MD
CathVision - Josef Kautzner, MD
Circle Cardiovascular Imaging - Saman Nazarian, MD
Drug Repurposing for AF - Mina Chung, MD
E-SAFE - Amin Al-Ahmad, MD
InCarda - Jeremy Ruskin, MD
Javelin Medical - Stuart Connolly, MD
RFMx - Andrea Natale, MD

Panel and Audience Discussion (20 minutes) - All Faculty

3:30-4:35 PM
XIV. CLINICAL OUTCOMES of CATHETER ABLATION for ATRIAL FIBRILLATION
Moderator: Srijoy Mahapatra, MD
Digital Moderator: John Day, MD

Impact of Catheter Ablation on Quality of Life and Health Care Utilization
Andrea Natale, MD

Impact of Catheter Ablation on Stroke, Cognitive Decline and Dementia
Jared Bunch, MD

Impact of Catheter Ablation on Congestive Heart Failure
Nassir Marrouche, MD

Impact of Catheter Ablation on Survival
David Wilber, MD

Impact of Catheter Ablation on Heart Failure Hospitalization in HFpEF
Moussa Mansour, MD

Panel and Audience Discussion (25 minutes) - All Faculty

4:35-5:30 PM
XV. PULMONARY VEIN ISOLATION: NEW TECHNIQUES and TECHNOLOGIES
Moderator: Meleze Hocini, MD
Digital Moderator: Elad Anter, MD

High-Power, Short Duration Temperature Controlled Ablation for AF
Moussa Mansour, MD

Cryo-Balloon Technologies for Pulmonary Vein Isolation
Karl-Heinz Kuck, MD

Radiofrequency Balloons for Pulmonary Vein Isolation
Amin Al-Ahmad, MD

Ultra-Low Temperature Linear Cryoablation for AF: Clinical Results
Tom DePotter, MD

Panel and Audience Discussion (20 minutes) - All Faculty

5:30-6:35 PM
XVI. PULSED FIELD ABLATION (PFA): Technology and Early Clinical Outcomes
Moderator: Dipen Shah, MD
Digital Moderator: Ravi Mandapati, MD

Pulsed Field Ablation Parameters: Determining Lesion Size
David Haines, MD

Insights into New Pulsed Field Ablation Technologies from Preclinical Research
Jacob Koruth, MD

Multielectrode Basket/Flower Array for PFA in Paroxysmal and Persistent AF
Pierre Jais, MD

Combined RF and Pulsed Field Ablation with Lattice Tip Catheter System
Vivek Reddy, MD

Single Pulse PFA with a Circular Mapping Catheter
Peter Loh, MD

Panel and Audience Discussion (25 minutes) - All Faculty

6:35-7:50 PM
XVII. CATHETER ABLATION for AF: BEYOND PULMONARY VEIN ISOLATION I
Moderator: Gregory Michaud, MD
Digital Moderator: Nassir Marrouche, MD

Multicenter Trial of Cryoablation for Persistent AF: STOP Persistent AF
Hugh Calkins, MD

Multicenter Trial of RF Catheter Ablation for Persistent AF: PRECEPT
Moussa Mansour, MD

Impact of Posterior Wall Isolation on the Success of Cryoablation for Persistent AF
Arash Aryana, MD

CONVERGE Study: Epi/Endo Ablation for Treatment of Persistent AF
David DeLurgio, MD

AF Ablation in Hypertrophic Cardiomyopathy
David Keane, MD, PhD

FDA Perspective on Catheter Ablation Trials for Persistent AF: A Changing Landscape
Jun Dong, MD

Panel and Audience Discussion (30 minutes) - All Faculty

9-10:05 PM
XVIII. CATHETER ABLATION for AF: BEYOND PULMONARY VEIN ISOLATION II
Moderator: Mark O’Neill, MD
Digital Moderator: Sanjiv Narayan, MD, PhD

Additional Ablation Targets Beyond PVI in Persistent AF
Luigi Di Biase, MD, PhD

Anatomically Guided Catheter Ablation for Persistent AF
Michel Haissaguerre, MD

Can We Identify AF Rotors by Catheter Mapping?
Hiroshi Nakagawa, MD, PhD

Advanced Technologies for Mapping of AF
Vivek Reddy, MD

Will Purkinje Pacing Lower the Threshold for Ablate and Pace?
Dan Lustgarten, MD

Panel and Audience Discussion (20 minutes) - All Faculty

10:05 AM-1:05 PM
XIX. REAL-TIME and PRERECORDED CASE TRANSMISSIONS III
Moderator: David Keane, MD, PhD
Digital Moderator: Moussa Mansour, MD
Panel: Rodney Horton, MD and Douglas Packer, MD

Renal Denervation for Atrial Fibrillation Using RF Energy
Alexander Romanov, MD, PhD and Evgeny Pokushalov, MD, PhD, State Research Institute of Circulation Pathology, Novosibirsk, Russia

Ultra-HF Ultrasound Based Renal Denervation for Atrial Fibrillation
Srinivas Dukkipati, MD and Vivek Reddy, MD, Mount Sinai School of Medical Center, New York, NY

3-D ICE with Left Atrial Appendage Closure
Vivek Reddy, MD and Petr Neuzil, MD, PhD, Homolka Hospital, Prague, Czech Republic

Pulsed Field Ablation for Atrial Fibrillation Using a Lattice-Tip Focal Catheter
Vivek Reddy, MD and Petr Neuzil, MD, PhD, Homolka Hospital, Prague, Czech Republic

Pulsed Field Ablation for Atrial Fibrillation Using a Conventional Focal Catheter
Ante Anic, MD, Split, Croatia

Pulsed Field Ablation for Persistent AF Using Single-Shot and Focal Catheters
Vivek Reddy, MD and Petr Neuzil, MD, PhD, Homolka Hospital, Prague, Czech Republic

Panel and Audience Discussions During Cases

1:05-1:25 PM
BREAK

1:25-2:30 PM
XX. INNOVATIONS in CATHETER ABLATION TECHNOLOGY and CLINICAL WORKFLOW
Supported by an educational grant from Medtronic
Moderator: Luigi Di Biase, MD
Digital Moderator: Atul Verma, MD

Preclinical Experience with a New Technology for Pulsed Field Ablation
Prashanthan Sanders, MD, PhD

Clinical Experience with a New Technology for Pulsed Field Ablation for AF
John Hummel, MD

Preclinical Experience with Diamond Temperature Controlled Irrigated RF Ablation
Thomas McElderry, MD

Clinical Experience with Diamond Temperature Controlled Irrigated RF Ablation
Josef Kautzner, MD, PhD

AF Ablation: Workflow Innovations in the Post COVID Environment
Suneet Mittal, MD

Panel and Audience Discussion (25 minutes) - All Faculty

2:30-2:40 PM
BREAK

2:40-3:45 PM
XXI. EARLY STAGE and EMERGING NEW TECHNOLOGIES and DRUGS in CARDIAC EP III
Moderator: Gerhard Hindricks, MD
Digital Moderator: Ravi Mandapati, MD

Kardium - Hans Kottkamp, MD
Manual Surgical Science - Douglas Gibson, MD
MedLumics - Atul Verma, MD
Parasym - Stavros Stavrakis, MD
ReCor - Vivek Reddy, MD
Volta Medical - Seth Goldbarg, MD
FDA Policy Update on Facilitating AF Device Innovation - Mark Fellman, BSME

Panel and Audience Discussion (25 minutes) - All Faculty

3:35-4:50 PM
XXII. OPTIMIZING the SAFETY of CATHETER PROCEDURES for ATRIAL FIBRILLATION
Moderator: David Keane, MD, PhD
Digital Moderator: Rodney Horton, MD

Atrio-Esophageal Fistula: Incidence, Management and Prevention
Thomas Deneke, MD

Managing Pericardial Effusions: Pharmacological and Non-Pharmacological Approaches
Srinivas Dukkipati, MD

New Technologies for Transseptal Puncture
Bradley Knight, MD

Strategies for Avoiding Vascular Access Complications in AF Ablation
Carola Gianni, MD

Tips and Tricks for Optimizing the Safety of AF Ablation
Richard Schilling, MD

Panel and Audience Discussion (25 minutes) - All Faculty

4:50-6:20 PM
XXIII. CHALLENGING CASES in AF MANAGEMENT
Case presentation and discussion - 10 minutes
Moderator: David Keane, MD, PhD
Presenters and Panel: John Day, MD, Moussa Mansour, MD, Francis Marchlinski, MD, Andrea Natale, MD, Douglas Packer, MD, Eric Prystowsky, MD, Jeremy Ruskin, MD and Jacqueline Saw, MD