7:15 AM
Welcome and Introduction

7:30-8:30 AM
AF Screening, Detection, Monitoring and AI in Cardiac Rhythm Management (60 minutes)
Moderators: Mintu Turakhia, MD and Elaine Hylek, MD
All lectures 7 minutes

Temporal Association Between Episodes of AF and Risk of Ischemic Stroke
Daniel Singer, MD

Population Screening for AF and Stroke Prevention: Stroke Stop and Other Studies
Mintu Turakhia, MD

The LOOP Study - Implications for Clinical Practice and Future Trials
Andrea Russo, MD

Wearable Technologies for AF Detection: The Fitbit Heart Study
Steven Lubitz, MD

AI-Enabled Algorithms for ECG Interpretation: Predicting AF Risk
Natalia Trayanova, MD

Panel and Audience Discussion (25 Minutes)

8:30-9:30 AM
SPOTLIGHT SESSION 1: Early Stage and Emerging New Technologies and Drugs in Cardiac EP (60 minutes)
Moderator: Srijoy Mahapatra, MD
All presentations 5 minutes

Electrographic Flow Mapping to Identify AF Sources (Ablacon)
David Haines, MD

Early Preclinical Data for A Novel High Heat-Ultrashort Duration PV Balloon (Aqua Heart)
Srijoy Mahapatra, MD

Complex AF Case Study Utilizing a New Standard in Signal Processing (BioSig Technologies)
DJ Lakkireddy, MD

Dynamically Referenced Navigation of Precision Therapy (CardioNXT)
Thomas Kurian, MD

The Clinical & Economic Value of Same Day Discharge of AF Ablation Patients using VASCADE MVP® (Cardiva Medical)
Walid Saliba, MD

Future of EP Recording with ECGenius (CathVision)
Mintu Turakhia, MD

Personalization AF Ablation Based on CT Wall Thickness (Circle Cardiovascular Imaging)
Saman Nazarian, MD

Clinical Experience with the CLAAS® LAAO System (Conformal Medical)
Jamie Kim, MD

The Latest in Tissue Lesion Assessment Capabilities for Ablation (EPD Solutions/Philips)
Lucas Boersma, MD

9:30-10 AM
BREAK (30 minutes)

10 AM-12:30 PM
Real-Time and Prerecorded Case Transmissions – Session 1
Moderators: Moussa Mansour, MD and Jeremy Ruskin, MD
Panel: Vivek Reddy, MD and Andrea Natale, MD

High-Power Ultra-Short Duration Ablation for AF
Mattias Duytschaever, MD, PhD, Sint Jan Hospital Bruges, Belgium

Pulsed Field Ablation for AF Using the 5S Strategy
Boris Schmidt, MD and Julian Chun, MD, Cardioangiologisches Centrum Bethanien, Frankfurt, Germany

Pulsed Field Ablation for AF Using an Integrated Mapping and Ablation Spherical Array Catheter
Vivek Reddy, MD and Petr Neuzil, MD, PhD, Homolka Hospital, Prague, Czech Republic

Surgical Left Atrial Appendage Exclusion
Dhanunjaya Lakkireddy, MD, Kansas City Heart Rhythm Institute, Kansas City, KS

AF Ablation Using a New Generation 3-D Electroanatomical Mapping System
Larry Chinitz, MD, NYU Langone Medical Center, New York, NY

12:30-1:30 PM
LUNCH (1 hour)

1:30-2:30 PM
AF Ablation and Stroke Risk Management
Supported by an Educational Grant from Abbott
Chairs: Elaine Hylek, MD and Nassir Marrouche, MD
All lectures 7 minutes

Does AF Ablation Reduce Stroke Risk?
Jeanne Poole, MD

Impact of AF Ablation on Cognitive Impairment and Dementia-New Data
Jared Bunch, MD

Clinical, Electrophysiologic and Procedural Determinants of Stroke Risk after AF Ablation
Nassir Marrouche, MD

Impact of Left Atrial Appendage Isolation on Stroke Risk after AF Ablation
Andrea Natale, MD

Optimal Timing of LAA Closure in Patients Undergoing AF Ablation
Claudio Tondo, MD, PhD

Panel & Audience Discussion (25 minutes)

2:30-3:30 PM
Left Atrial Appendage Closure and Stroke Prevention
Supported by an Educational Grant from Boston Scientific
Moderators: Douglas Gibson, MD and Devi Nair, MD
All lectures 7 minutes

Safety and Efficacy of LAA Closure: Insights from the PINNACLE Study
Shephal Doshi, MD

Peri and Post Procedural Anticoagulation with LAA Closure Devices - An Evolving Story
Luigi Di Biase, MD

New Frontiers in Indications for LAA Closure - LAAC Plus or Versus DOACs
Ken Ellenbogen, MD

Left Atrial Appendage Closure in Patients with Prohibitive Anatomy
Christopher Ellis, MD

Unmet Needs and Future Directions in LAA Closure Technologies: Antithrombotics/Drug Eluting Devices/Deflectable Sheaths
Walid Saliba, MD

Panel and Audience Discussion (25 minutes)

3:30-4 PM
BREAK (30 minutes)

4-5 PM
Stroke Prevention in AF - Left Atrial Appendage Closure
Moderators: JDouglas Gibson, MD and Devi Nair, MD
All lectures 7 minutes

Amplatzer Amulet Left Atrial Appendage Occluder Vs Watchman Device for Stroke Prophylaxis
DJ Lakkireddy, MD

Simplifying LAA Closure with ICE and CT Imaging
Devi Nair, MD

Clinical Implications of Peri-Device Leaks after LAA Closure
Moussa Mansour, MD

Complications of LAA Closure Including Device Related Thrombus
Jacqueline Saw, MD

Does LAA Closure Impact Hard Endpoints: Stroke and Mortality?
Vivek Reddy, MD

Panel and Audience Discussion (25 minutes)

7:20 AM
Welcome

7:30-8:30 AM
Early Rhythm Control in Atrial Fibrillation (60 minutes)
Moderators: Gregory Michaud, MD and Luigi Di Biase, MD, PhD
All lecturers 7 minutes

Early Rhythm Control in Asymptomatic AF- New Data from EAST-AFNET 4
Stephan Willems, MD

Who Should Have Catheter Ablation as First Line Therapy for AF?
Oussama Wazni, MD

Do the Outcomes of Early Rhythm Control in PAF Extend to Patients with Persistent AF or Do We Need More Studies?
Karl-Heinz Kuck, MD

Does the Presence of HFpEF Alter the Threshold for Early AF Ablation? Francis Marchlinski, MD

In Which Populations Does AF Ablation Improve Survival?
Douglas Packer, MD

Panel and Audience Discussion (25 minutes)

8:30-9:30 AM
SPOTLIGHT SESSION 2: Early Stage and Emerging New Technologies and Drugs in Cardiac EP (60 minutes)
Moderators: Paul Wang, MD
All lectures 5 minutes

A Novel Single-Shot Catheter for PVI (ElectroPhysiology Frontiers)
Jonathan Piccini, MD

HEARTguide the Novel LAAO Preoperative Planning (FEops)
Jacqueline Saw, MD

The Globe PF System: A Complete Solution for High-Definition Mapping and Pulsed-Field Ablation for AF (Kardium)
Atul Verma, MD

Esophageal Protection Using the DV8 Retractor (Manual Surgical Science)
Rahul Bhardwaj, MD

First Experience with an AI-Based System for Invasive AF Therapy (NeuTrace)
Andrea Natale, MD

Ultrasound Renal Denervation for Atrial Fibrillation (ReCor Medical)
Vivek Reddy, MD

Early Clinical Experience with Persistent AF Ablation (Volta Medical)
Seth Goldbarg, MD

9:30-10 AM
BREAK (30 minutes)

10 AM-12:30 PM
Real-Time and Prerecorded Case Transmissions – Session 2
Moderators: Moussa Mansour, MD and David Keane, MD, Ph
Panel: Christopher Ellis, MD and Pasquale Santangeli, MD

Pulsed Field Ablation Using a Circular Multielectrode Catheter
Tom De Potter, MD, OLV Hospital, Aalst, Belgium

Mitral Isthmus Ablation with Ethanol Injection in The Vein of Marshall in Persistent AF
Vivek Reddy, MD, Mount Sinai Medical Center, New York, NY

Pulsed Field Ablation Using a Multielectrode Catheter
Moussa Mansour, MD, Massachusetts General Hospital, Boston, MA

AF/AFL Ablation Guided by 4-D ICE and High-Density Mapping
Brett Gidney, MD, Marian Regional Medical Center, Santa Maria, CA

LAA Closure Using the Watchman FLX
Rodney Horton, MD and Amin Al-Ahmad, MD, Texas Cardiac Arrhythmia Institute, Austin, TX

12:30-1:30 PM
LUNCH (1 Hour)

1:30-2:30 PM
Evolving Trends in Catheter Ablation for Atrial Fibrillation
Supported by an educational grant from Biosense Webster
Moderators: Paul Zei, MD and Devi Nair, MD
All lectures 7 minutes

High Resolution AF Mapping for Electrogram Characterization for Mapping Ablation Gaps
Elad Anter, MD

Atrial Fibrillation Radiofrequency Catheter Ablation Guided by the VISITAG SURPOINT Module
Luigi Di Biase, MD, PhD

The Journey to Lab and Procedural Efficiency and Same-Day Discharge
Amit Thosani, MD

Lessons from Large Ablation Databases on AF Ablation
Jose Osorio, MD

Racial, Ethnic and Sex Differences in AF: How to Achieve Health Equity for All Patients
Larry Jackson, MD

Panel Discussion (25 minutes) - All Faculty

2:30-3:30 PM
New Directions in AF Management: The Impact of First-Line Indication and Innovations in Catheter Ablation Technology
Supported by an educational grant from Medtronic
Moderators: Pasquale Santangeli, MD and Atul Verma, MD
All lectures 7 minutes

Cryoablation as First-Line Treatment (Meta-Analysis of Clinical Trials)
Jason Andrade, MD

Can AF Ablation be Performed at Centers Without Surgical Backup?
Jason Zagrodzky, MD

Role of Cryoablation for Persistent Atrial Fibrillation
Anish Amin, MD

Is Contact Force Sensing Necessary with Temperature Controlled Ablation – New Preclinical Evidence
Atul Verma, MD

Temperature Controlled Ablation – Practical Lessons from DIAMOND AF I
Jose Osorio, MD

Panel and Audience Discussions (25 Minutes) - All Faculty

3:30-4 PM
BREAK (30 minutes)

4-5:30 PM
LATE-BREAKING CLINICAL TRIALS, FIRST-REPORT CLINICAL INVESTIGATIONS and BEST ABSTRACT AWARD
Moderator: Moussa Mansour, MD

5:30-7 PM
Challenging Cases in AF Management (Drugs, Ablation, and Stroke Prevention) 90 minutes (6 cases: 5 min per case; 10 min discussion)
Moderator: David Keane, MD, PhD
Faculty: John Camm, MD, John Day, MD, David Keane, MD, PhD, Young-Hoon Kim, MD, PhD, Gregory Michaud, MD, Eric Prystowsky, MD

7 AM
Welcome

7:30-8:30 AM
Pulsed Field Ablation: Mechanisms and Technologies
Moderators: Hugh Calkins, MD and David Keane, MD, PhD
All lectures 7 minutes

Mechanisms of Pulsed Field Ablation and Impact of Parameter Selection and Electrode Configuration
David Haines, MD

Tissue Selectivity of Pulsed Field Ablation: Determinants and Limitations
Damijan Miklavcic, MD

New Preclinical Observations on Pulsed Field Ablation and Determinants of Reversibility
Jacob Koruth, MD

Technology and Regulatory Status of Current Systems for Pulsed Field Ablation
Moussa Mansour, MD

Future Directions in Pulsed Field Ablation - Technologies and Applications
Vivek Reddy, MD

Panel and Audience Discussion (25 minutes)

8:30-9:30 AM
Pulsed Field Ablation for Atrial Fibrillation
Moderators: Vivek Reddy, MD and Gerhard Hindricks, MD
All lectures 7 minutes.

Durability of Pulmonary Vein Isolation with Pulsed Field Ablation
Srinivas Dukkipati, MD

Long term Outcomes of Pulsed Field Ablation for Atrial Fibrillation
Pierre Jais, MD

Role of Pulsed Field Ablation in Non-Pulmonary Vein Ablation in AF
Ante Anic, MD

Impact of PFA on the Efficiency of AF Ablation - Are We on the Verge of 10-minute PVI Procedures?
Andrea Natale, MD

Potential Safety Concerns with Pulsed Field Ablation
Meleze Hocini, MD

Panel and Audience Discussion (25 minutes)

9:30-10 AM
BREAK (30 minutes)

10 AM-12:30 PM
Real Time and Prerecorded Case Transmissions – Session 3
Moderators: Moussa Mansour, MD and Andrea Natale, MD
Panel: Vivek Reddy, MD

Pulsed Field Ablation Using a Multielectrode Catheter
Petr Neuzil, MD, PhD, Homolka Hospital, Prague, Czech Republic

LAA Closure Using the Amulet Device
Dhanunjaya Lakkireddy, MD, Kansas City Heart Rhythm Institute, Kansas City, KS

Pulsed Field Ablation Using a Focal Electrode Catheter
Atul Verma, MD, Southlake Regional Health Centre, Toronto ON

Combined Pulsed Field & Cryo Ablation for AF
Atul Verma, MD, Southlake Regional Health Centre, Toronto ON

Focal Pulsed Field Ablation Guided by Contact & Noncontact Mapping
Petr Neuzil, MD, PhD, Homolka Hospital, Prague, Czech Republic

12:30-1:30 PM
LUNCH (1 hour)

1:30-2:30 PM
Beyond Pulmonary Vein Isolation
Moderators: Gerhard Hindricks, MD and Luigi Di Biase, MD, PhD
All lectures 7 minutes

Lifestyle Interventions and AF Ablation - What is the Data?
Gerhard Hindricks, MD

Targeting Atrial Fibrosis: Results and Clinical Implications of DECAAF II
Nassir Marrouche, MD

Role of Coronary Sinus and Mitral Isthmus Ablation in Persistent AF
Thomas Pambrun, MD

Adjunctive LAA Ligation in AF Ablation: The AMAZE Trial
David Wilber, MD

Future Clinical Trials for Ablation of Persistent AF - Are There Mechanism Driven Design Options?
Hugh Calkins, MD

Panel and Audience Discussion (25 minutes)

3 PM
Symposium Adjourns